In this case, we wanted to use stem cells (MSCs) to treat damaged and hard-to-repair lung injury cells (e.g. Covid sequelae).

Previously, most scholars have used PCR to detect human DNA or immunostaining to identify human-specific nuclear proteins, but neither of these approaches can show the biodistribution of stem cells and quantitative information to assess the efficacy and safety of the drug in vivo.

When implementing large animal injury models, especially in pigs, which have many similarities to human physiology, a more accurate assay is critical, and therefore LTK was used as an important basis for tracking stem cells in this case.

The image on the right is a composite image of a pig lung section in bright view and LTK fluorescence taken by our exclusive technique. The red dots pointed by the black arrows are the originally identified stem cells (MSCs), and the migration of stem cells was successfully observed using this technique.